The U.S. attacks were the ninth consecutive day of bombing since peace talks between the two countries collapsed in dispute over a memorandum of understanding focused on the Strait of Hormuz.
The United States and Iran exchanged strikes aimed at infrastructure and military targets on Saturday as their battle over the Strait of Hormuz intensified.
Recognizing Iran's control over the Strait of Hormuz could set a dangerous precedent, with other countries attempting to claim important waterways, analysts say.
The U.S. and Iran expanded their targets in the latest round of strikes on Friday, as fighting over the control of the Strait of Hormuz reignites fears of an all-out war.
Iran threatened to block all oil exporting routes in the region on Wednesday in response to the U.S. maritime blockade of Iranian ports in the Strait of Hormuz.
The U.S. military announced it will begin its blockade of Iranian ships over the Strait of Hormuz on Tuesday, as Iran vowed to assert its own control over the critical international waterway.
The regional crossfire raised the risks that an interim agreement to halt fighting in the war could break down, putting the Middle East again at risk of a wider conflict.
U.S. and Iranian negotiators met separately on Wednesday with Qatari and Pakistani mediators, with "positive progress made," and they agreed to continue discussions, host Qatar said.
President Trump said talks with Iran would resume Tuesday in Qatar, despite the two sides trading attacks in the Gulf over the weekend. Iran did not confirm whether it will participate.
The U.S. struck Iran on Friday in response to a drone attack a day earlier on a cargo ship in the Strait of Hormuz. It's the most significant test yet to an interim understanding reached a week ago by the two countries.
A United Nations agency paused the evacuation of ships through the Strait of Hormuz on Thursday after the British military said a vessel was hit by a projectile off the coast of Oman following the passage of several tankers that used a route backed by the U.N.