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News Articles: crispr

KJ Muldoon, who was born at Children's Hospital of Philadelphia in August, reaches out to doctors after being treated for a rare genetic disorder using CRISPR technology.

Tagged as: 

  • Health

A promising genetic treatment tailor-made for a baby born with a rare disorder

For the first time, doctors have created a customized treatment using the revolutionary gene-editing technique known as CRISPR to treat a baby with a rare, life-threatening genetic disorder.

May 15, 2025
|
By:
  • Rob Stein
Geri Landman and her daughter Lucy.

Tagged as: 

  • Health

For kids with rare genetic disorders, customized CRISPR treatments offer hope

The gene-editing technique is effective for treating some illnesses but it's been too expensive to consider it for rare conditions. A new approach in the works could make it more widely available.

December 13, 2024
|
By:
  • Rob Stein
"The therapy has really transformed my life more than I could have ever imagined," Victoria Gray, the first person to receive the CRISPR gene-editing treatment tellls NPR. "It gave me a new lease on life."

Tagged as: 

  • Health

Sickle cell patient's journey leads to landmark approval of gene-editing treatment

In early December, the Food and Drug Administration approved a gene-editing treatment for sickle cell disease, the first for any illness. One patient helped pave the way.

December 25, 2023
|
By:
  • Rob Stein
Preliminary results from a study show that gene-editing technology can be used to successfully treat a genetic disorder that increases the risk of heart disease.

Tagged as: 

  • Health

For the first time, gene-editing provides hints for lowering cholesterol

Researchers report the first results from a study testing the revolutionary gene-editing technique known as CRISPR for cutting high cholesterol.

November 13, 2023
|
By:
  • Rob Stein
"It's really life-changing," says Victoria Gray, when describing the gene-editing treatment for sickle cell disease that she received as part of a clinical trial in 2019.

Tagged as: 

  • Health

FDA advisers see no roadblocks for gene-editing treatment for sickle cell disease

Advisers to the Food and Drug Administration meeting Tuesday paved the way for the first treatment of human disease using the gene-editing technique CRISPR. The agency has a December deadline.

October 31, 2023
|
By:
  • Rob Stein
Scientists have engineered an albino squid that provides a window into the inner workings of the brain.

Tagged as: 

  • News

How scientists engineered a see-through squid with its brain in plain view

A see-through squid is giving scientists an unprecedented view of the brain and other organs in a living animal.

August 28, 2023
|
By:
  • Jon Hamilton
Mosquitoes spread malaria. Now researchers hope that a gene drive technology could turn them into malaria fighters. Although not every scientist thinks it's a good idea to genetically modify a wild animal.

Tagged as: 

  • Global Health

Mosquitoes spread malaria. These researchers want them to fight it instead

Scientists have used a gene-editing technique to make mosquitos allies in the fight against malaria. Environmentalists are troubled by the idea of genetically modifying wild animals.

July 20, 2023
|
By:
  • Geoff Brumfiel
He Jiankui announced nearly five years ago that he had created the first gene-edited babies.

Tagged as: 

  • World

His baby gene editing shocked ethicists. Now he's in the lab again

He Jiankui, who shocked the world in 2018 by announcing the creation of the first gene-edited babies, tells NPR he's now working on a cure for Duchenne muscular dystrophy.

June 08, 2023
|
By:
  • John Ruwitch
In London to address a gene-editing summit last week, Victoria Gray took a break to visit Sir John Soane's Museum. In 2019, Gray became the first patient to be treated for sickle cell disease using CRISPR, an experimental gene-editing technique. She was invited to talk about her experiences at the Third International Summit on Human Genome Editing.

Tagged as: 

  • Health

Sickle cell patient's success with gene editing raises hopes and questions

A Mississippi woman's life has been transformed by a treatment for sickle cell disease with the gene-editing technique CRISPR. All her symptoms from a disease once thought incurable have disappeared.

March 16, 2023
|
By:
  • Rob Stein
Researchers meeting in London this week concluded that techniques that have made it easier to manipulate DNA still produce too many mistakes for scientists to be confident any children born from edited embryos (such as these, photographed in 2018) would be healthy.

Tagged as: 

  • Health

Ethical concerns temper optimism about gene-editing for human diseases

The Third International Summit on Genome Editing concluded Monday with ethicists warning scientists to slow down efforts to use gene-editing to enhance the health of embryos.

March 10, 2023
|
By:
  • Rob Stein
Biophysicist He Jiankui addressed the last international summit on human genome editing in Hong Kong in 2018. His experiments in altering the genetic makeup of human embryos was widely condemned by scientists and ethicists at the time, and still casts a long shadow over this week's summit in London.

Tagged as: 

  • Health

Experts weigh medical advances in gene-editing with ethical dilemmas

The last time this summit convened in 2018, the world was shocked to hear a scientist had created the first gene-edited babies. He was condemned, but gene-editing has continued, with some success.

March 07, 2023
|
By:
  • Rob Stein
Katie Pope Kopp, 64, of Parkville, Mo., at Union Station in Kansas City this week. Kopp underwent a new form of experimental CAR T-cell therapy that used the CRISPR gene-editing technique to treat her non-Hodgkin lymphoma. The cancer has been in remission for over a year.

Tagged as: 

  • Health

CRISPR gene-editing may boost cancer immunotherapy, new study finds

Using CRISPR to modify certain immune cells could make cancer-fighting immunotherapy more potent for a broader set of patients. Two people who went through the treatment share their stories.

December 13, 2022
|
By:
  • Rob Stein
Carlene Knight, who has a congenital eye disorder, volunteered to let doctors edit the genes in her retina using CRISPR.

Tagged as: 

  • Health

A Gene-Editing Experiment Let These Patients With Vision Loss See Color Again

In a first, doctors injected the gene-editing tool CRISPR directly into cells in patients' eyes. The experiment helped these vision-impaired patients see shapes and colors again.

September 29, 2021
|
By:
  • Rob Stein
Patrick Doherty volunteered for a new medical intervention of gene-editor infusions for the treatment of genetically-based diseases.

Tagged as: 

  • Health

He Inherited A Devastating Disease. A CRISPR Gene-Editing Breakthrough Stopped It

Scientists successfully treated a rare disease with the experimental gene-editing technique. It could open the door to new ways of treating more common disorders in the future.

June 28, 2021
|
By:
  • Rob Stein
Carlene Knight, 54, is one of the first patients in a landmark study designed to try to restore vision in those who have a rare genetic disease that causes blindness.

Tagged as: 

  • Health

Blind Patients Hope Landmark Gene-Editing Experiment Will Restore Their Vision

The unprecedented study involves using the gene-editing technique CRISPR to edit a gene while it's still inside a patient's body. In exclusive interviews, NPR talks with two of the first participants.

May 10, 2021
|
By:
  • Rob Stein
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